Topic
Nutrition science, metabolic health, glucose, fasting, insulin sensitivity, and evidence-based dietary research.
A cross-sectional study of 61 healthy young women found that the gut microbiome’s genetic capacity for certain metabolic pathways was associated with GABA, glutamate and excitatory/inhibitory balance in distinct brain regions. The findings also linked some microbial pathways with anxiety, depressive symptoms and sleep quality, but did not establish cause and effect.
A study from Sanford Burnham Prebys and collaborating institutions found that elevated glucose thickened the glycocalyx—a sugar-rich coating on cancer cells—under laboratory conditions designed to resemble the tumor environment. The effect depended on HSF1, suggesting a possible research path for making cancer cells more visible to immune defenses, though no human treatment benefit was established.
Updated American Heart Association/American Stroke Association guidance highlights rehabilitation that may begin within days of a stroke and address movement, communication, cognition, sleep, nutrition and mental health. The guidance also emphasizes that recovery is often a long-term process involving survivors, caregivers and a multidisciplinary care team.
A study of mice linked sucralose and stevia exposure with changes in gut bacteria, glucose regulation and gene activity. Some findings remained in descendants that had never consumed the sweeteners, although the researchers emphasized that the results do not establish direct causation or show that the same effects occur in humans.
Researchers tested gene therapy delivering the bacterial enzyme LplA in Caenorhabditis elegans and mice. The intervention increased protein lipoylation, improved measures of energy metabolism, and lowered reactive oxygen species in the reported models, while also being associated with better movement, stress resistance, and delayed age-related decline.
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