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Caspase-1 Inhibitor Reduced Lung Tumors in Mice, MIT Study Finds
An MIT-led preclinical study found that blocking the inflammatory enzyme caspase-1 reduced the number and size of lung tumors in genetically engineered mice. The researchers also detected higher caspase-1 activity in a small set of human lung-fluid samples from patients with lung cancer, but the proposed preventive use has not yet been tested in people.
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