José A. Nicolás-Ávila

Mouse Study Finds High-Energy Tissues Build Larger Mitochondrial Cleanup Teams

A study in Science Immunology found that heart muscle, skeletal muscle and brown fat in mice maintain larger populations of macrophages as their energy demands and mitochondrial waste increase. The researchers also reported a similar relationship in publicly available human muscle-cell datasets, but the human analysis did not establish that the system causes changes in tissue function.